Testosterone was the first ever synthesized anabolic steroid. Testosterone enanthate is a slow-acting, long-ester, oil-based injectable testosterone compound that is commonly prescribed for the treatment of hypogonadism – low testosterone levels and various related symptoms in males.
The Enanthate Ester: An ester is any of a class of organic compounds that react with water to produce alcohols and organic or inorganic acids. Most esters are derived from carboxylic acids, and injectable testosterone is typically administered along with one or multiple esters. The addition of a carbon chain (ester) attached to the testosterone molecule controls how soluble it will be once inside the bloodstream. The smaller the carbon chain, the shorter the ester, and the more soluble the medication. A small/short ester will have a shorter half life – a repeating cycle of a medication’s time and activity within the body.
The inverse is true of long carbon chains, like enanthate, which both act slowly upon the body and evacuates the body at a similar rate. Specifically, testosterone enanthate contains the carboxylic acid ester (enanthoic acid), and a half-life is approximately 8-9 days; the longest half-life of all common ester based testosterones. An uncommon testosterone such as Nebido (testosterone undecanoate) has a very long 3-month half-life.
Testosterone Enanthate is one of the oldest and perhaps the most commonly used anabolic steroid of all time. Testosterone Enanthate is a slow acting release form of the testosterone hormone and would be the first large/long ester testosterone form used. Synthetic testosterone itself would be developed in the 1930’s. The first batches of testosterone manufactured would have no ester attached (Testosterone Suspension) and needless to say would be fast acting and require very frequent injections.
In 1937 the first ester controlled testosterone would hit the market thanks to Schering and their new Testosterone Propionate product. This would allow for more control over the testosterone hormone by regulating its time release.
However, in the early 1950’s a larger ester in Enanthate would be attached to the hormone thereby slowing down the hormone’s activity even more. Testosterone Enanthate would become the dominating testosterone form in the medical field and Testosterone Cypionate would join a few years later. The difference in Testosterone Enanthate and Testosterone Cypionate is largely inconsequential.
Testosterone Enanthate Uses:
Testosterone Enanthate is used in men who do not make enough of a natural substance called testosterone. In males, testosterone is responsible for many normal functions, including growth and development of the genitals, muscles, and bones. Testosterone Enanthate also helps cause normal sexual development (puberty) in boys. Testosterone belongs to a class of drugs known as androgens. It works by affecting many body systems so that the body can develop and function normally.
Testosterone Enanthate may also be used in certain adolescent boys to cause puberty in those with delayed puberty. It may also be used to treat certain types of breast cancer in women.